Israel launches Gaza offensive, kills Hamas commander

GAZA (Reuters) - Israel launched a major offensive against Palestinian militants in Gaza on Wednesday, killing the military commander of Hamas in an air strike and threatening an invasion of the enclave that the Islamist group vowed would "open the gates of hell".


The onslaught shattered hopes that a truce mediated on Tuesday by Egypt could pull the two sides back from the brink of war after five days of escalating Palestinian rocket attacks and Israeli strikes at militant targets.


Operation "Pillar of Defence" began with a surgical strike on a car carrying the commander of the military wing of Hamas, the Iranian-armed Islamist movement which controls Gaza and dominates a score of smaller armed groups.


Within minutes of the death of Ahmed Al-Jaabari, big explosions were rocking Gaza, as the Israeli air force struck at selected targets just before sundown, blasting plumes of smoke and debris high above the crowded city.


Panicking civilians ran for cover and the death toll mounted quickly. Nine people including three children were killed, the health ministry said, and about 40 people were wounded.


Army tanks shelled border areas of Gaza in south and the Israeli navy shelled a Hamas security position from the sea.


Hamas stuck back, firing at least four Grad rockets at the southern city of Beersheva in what it called its initial response. Israel reported damage but no casualties.


The escalation in Gaza came in a week when Israel fired at Syrian artillery positions it said had fired into the Israeli-annexed Golan Heights amid a civil war in Syria that has brought renewed instability to Lebanon.


Egypt, whose new Islamist government is still honoring the 1979 peace agreement with Israel, condemned the raids on Gaza as a threat to regional security and withdrew its ambassador from Israel. It also summoned the Israeli envoy to Cairo to deliver a protest and called for an emergency meeting of the United Nations Security Council.


Russia called for an end to the raids.


A second Gaza war has loomed on the horizon for months as waves of Palestinian rocket attacks and Israeli strikes grew increasingly more intense and frequent.


Israel's Operation Cast Lead in 2008-2009 began with a week of air attacks and shelling, followed by a land invasion of the blockaded coastal strip, sealed off at sea by the Israeli navy. Some 1,400 Palestinians were killed and 13 Israelis died.


KILLED IN HIS CAR


Hamas said Jaabari, who ran the organization's armed wing, Izz el-Deen Al-Qassam, died along with a Hamas photographer when their car was blown apart by an Israeli missile.


The charred wreckage of a car could be seen belching flames, as emergency crews picked up what appeared to be body parts.


Israel confirmed it had carried out the attack and announced there was more to come. Reuters witnesses saw Hamas security compounds and police stations blasted apart.


"Today we relayed a clear message to the Hamas organization and other terrorist organizations," Prime Minister Benjamin Netanyahu said. "And if there is a need, the IDF (Israel Defence Forces) is prepared to broaden the operation. We will continue to do everything in order to protect our citizens."


Immediate calls for revenge were broadcast over Hamas radio.


"The occupation has opened the gates of hell," Hamas's armed wing said. Smaller groups also vowed to strike back.


"Israel has declared war on Gaza and they will bear the responsibility for the consequences," Islamic Jihad said.


Southern Israeli communities within rocket range of Gaza were on full alert, and schools were ordered closed for Thursday. About one million Israelis live in range of Gaza's relatively primitive but lethal rockets, supplemented in recent months by longer-range, more accurate systems.


"The days we face in the south will, in my estimation, prove protracted," Brigadier-General Yoav Mordechai, Israel's chief military spokesman, told Channel 2 TV.


"The home front must brace itself resiliently."


Mordechai said Israel was both responding to a surge in Palestinian rocket salvoes earlier this week and trying to prevent Hamas and other Palestinian factions from building up their arsenals further.


Among the targets of Wednesday's air strikes were underground caches of longer-range Hamas rockets, he said.


Asked if Israel might send in ground forces, Mordechai said: "There are preparations, and if we are required to, the option of an entry by ground is available."


OBAMA BRIEFED


Israeli President Shimon Peres briefed U.S. President Barack Obama on the operation, Peres's office said in a statement. He told Obama that Jaabari was a "mass-murderer" and his killing was Israel's response to Palestinian rocket attacks from Gaza.


"Israel is not interested in stoking the flames, but for the past five days there has been constant missile fire at Israel and mothers and children cannot sleep quietly at night," said Peres, who visited the border town of Sderot earlier.


In the flare-up that was prelude to Wednesday's offensive, more than 115 missiles were fired into southern Israel from Gaza and Israeli planes launched numerous strikes.


Seven Palestinians, three of them gunmen, were killed. Eight Israeli civilians were hurt by rocket fire and four soldiers wounded by an anti-tank missile.


Palestinian President Mahmoud Abbas asked Arab League Secretary General Nabil al-Arabi to call an emergency meeting of the League's Council to denounce "dangerous Israeli escalation and brutal aggression on our people in the Gaza Strip".


The leader of Hamas in the Gaza Strip, Ismail Haniyeh, called on Arab states, especially Egypt, to halt the assault.


Egypt's foreign ministry condemned the Israeli strikes, saying any further escalation "could have negative repercussions on the security and stability of the region".


Israel's intelligence agency Shin Bet said Jaabari led Hamas' takeover of Gaza in 2007, when the militant Islamist group ousted fighters of the Fatah movement of its great rival, the Western-backed Palestinian president Mahmoud Abbas.


It said he instigated the attack that led to the capture of Israeli Corporal Gilad Shalit in a kidnap raid from Gaza in 2006. Jaabari was also the man who handed Shalit over to Israel in a prisoner exchange five years after his capture.


Israel holds a general election on January 22 and Netanyahu has pledged to retaliate harshly against Hamas. But Israel is also wary of the reaction from Mursi's Egypt, whose ruling Muslim Brotherhood is the spiritual mentor of Hamas.


Hamas has been emboldened by its rise to power, viewing Mursi as a "safety net" who will not permit a second Israeli thrashing of Gaza, home to 1.7 million Palestinians.


Hamas is also supported by Iran, which Israel regards as a rising threat to its own existence due to its nuclear program.


Helped by the contraband trade through tunnels from Egypt, Gaza militias have smuggled in better weapons.


But their estimated 35,000 Palestinian fighters are still no match for Israel's F-16 fighter-bombers, Apache helicopter gunships, Merkava tanks and other modern weapons systems in the hands of a conscript force of 175,000, with 450,000 in reserve.


(Additional reporting by Dan Williams, Crispian Balmer and Ori Lewis in Jerusalem; Writing by Douglas Hamilton; Editing by Giles Elgood)


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Zynga CFO leaves for Facebook
















SAN FRANCISCO (Reuters) – Zynga Inc‘s chief financial officer, David Wehner, will leave the company for an executive position at Facebook Inc, the gaming company announced Tuesday as it reshuffled its upper ranks.


David Ko, chief mobile officer, has been elevated to become Zynga‘s new chief operations officer.













Mark Vranesh, Zynga’s top accounting executive, will replace Wehner as CFO, Zynga said.


(Reporting By Gerry Shih; Editing by Steve Orlofsky)


Gaming News Headlines – Yahoo! News



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Bradley Cooper on Jennifer Lawrence's Comedy Chops

Bradley Cooper appears in the offbeat film Silver Linings Playbook with Jennifer Lawrence and he says the Oscar-nominated actress does a great job showcasing her comedy skills in a compelling role as a sex addict.

Speaking at a New York screening of the film on Monday night, Bradley said the Hunger Games star was "incredible" in the role. "Actually if you know her at all, she's closest to this role I think in her real life," he said. "She's very funny and her timing in incredible, she's very off-the-cuff and you never really know what to expect, in a wonderful way."

VIDEO: Jennifer Lawrence On Bradley Cooper & Playing a Sex Addict

Bradley responded to comments made by Jennifer that he actually picked up the film's dance routines faster than she did. "Well, I had a lot easier time because the woman usually has the brunt of all the hard moves, so she really worked her tail off.' He also laughed off Jennifer's suggestion that he could someday win Dancing with the Stars.

VIDEO: Jennifer Lawrence on Her Kinship with Bradley Cooper

Silver Linings Playbook -- hitting theaters November 21 -- stars Bradley as Pat Solatano, a grown man living with his mother (Jacki Weaver) and father (Robert De Niro) after losing his house, job and wife -- and spending eight months in a state institution on a plea bargain. Determined to rebuild his life and reunite with his wife, Pat meets a mysterious girl named Tiffany (Jennifer), who has her own set of issues, but offers to help him reconnect with his wife if he'll do something very important in return.

VIDEO: Bradley Cooper Suggests the Next 'Sexiest Man Alive' 

Watch the video to also learn about Julia Stiles' role and to hear Chris Tucker talk about working with the film's talented cast.

Read More..

Report: FDA wanted to close Mass pharmacy in 2003

WASHINGTON (AP) — Nearly a decade ago, federal health inspectors wanted to shut down the pharmacy linked to a recent deadly meningitis outbreak until it cleaned up its operations, according to congressional investigators.

About 440 people have been sickened by contaminated steroid shots distributed by New England Compounding Center, and more than 32 deaths have been reported since the outbreak began in September, according to the Centers for Disease Control and Prevention. That has put the Framingham, Mass.-based pharmacy at the center of congressional scrutiny and calls for greater regulation of compounding pharmacies, which make individualized medications for patients and have long operated in a legal gray area between state and federal laws.

The House Energy and Commerce Committee released a detailed history of NECC's regulatory troubles on Monday, ahead of a meeting Wednesday meeting to examine how the outbreak could have been prevented. The 25-page report summarizes and quotes from FDA and state inspection reports and internal memos, though the committee declined to release the original documents.

The report shows that after several years of problems, Food and Drug Administration officials in 2003 suggested that the compounding pharmacy be "prohibited from manufacturing" until it improved its operations. But FDA regulators deferred to their counterparts in Massachusetts, who ultimately reached an agreement with the pharmacy to settle concerns about the quality of its prescription injections.

The congressional report also shows that in 2003 the FDA considered the company a pharmacy. That's significant because since the outbreak came to light in late September, public health officials have charged that NECC was operating more as a manufacturer than a pharmacy, shipping thousands of doses of drugs to all 50 states instead of small batches of drugs to individual patients. Manufacturers are regulated by the FDA and are subject to stricter quality standards than pharmacies.

The report offers the most detailed account yet of the numerous regulatory complaints against the pharmacy, which nearly date back to its founding in 1998. Less than a year later, the company was cited by the state pharmacy board for providing doctors with blank prescription pads with NECC's information. Such promotional items are illegal in Massachusetts and the pharmacy's owner and director, Barry Cadden, received an informal reprimand, according to documents summarized by the committee.

Cadden was subject to several other complaints involving unprofessional conduct in coming years, but came to the FDA's attention in 2002. Here are some key events from the report highlighting the company's early troubles with state and federal authorities:

__ In March of 2002 the FDA began investigating reports that five patients had become dizzy and short of breath after receiving NECC's compounded betamethasone repository injection, a steroid used to treat joint pain and arthritis that's different from the one linked to the current meningitis outbreak.

FDA inspectors visited NECC on April 9 and said Cadden was initially cooperative in turning over records about production of the drug. But during a second day of inspections, Cadden told officials "that he was no longer willing to provide us with any additional records," according to an FDA report cited by congressional investigators. The inspectors ultimately issued a report citing NECC for poor sterility and record-keeping practices but said that "this FDA investigation could not proceed to any definitive resolution," because of "problems/barriers that were encountered throughout the inspection."

__ In October of 2002, the FDA received new reports that two patients at a Rochester, N.Y., hospital who came down with symptoms of bacterial meningitis after receiving a different NECC injection. The steroid, methylprednisolone acetate, is the same injectable linked to the current outbreak and is typically is used to treat back pain. Both patients were treated with antibiotics and eventually recovered, according to FDA documents cited by the committee.

When officials from the FDA and Massachusetts Board of Pharmacy visited NECC later in the month, Cadden said vials of the steroid returned by the hospital had tested negative for bacterial contamination. But when FDA scientists tested samples of the drug collected in New York they found bacterial contamination in four out of 14 vials sampled. It is not entirely clear whether FDA tested the same lot shipped to the Rochester hospital.

__ At a February 2003 meeting between state and federal officials, FDA staff emphasized "the potential for serious public consequences if NECC's compounding practices, in particular those relating to sterile products, are not improved." The agency issued a list of problems uncovered in its inspection to NECC, including a failure to verify if sterile drugs met safety standards.

But the agency decided to let Massachusetts officials take the lead in regulating the company, since pharmacies are typically regulated at the state level. It was decided that "the state would be in a better position to gain compliance or take regulatory action against NECC as necessary," according to a summary of the meeting quoted by investigators.

The FDA recommended the state subject NECC to a consent agreement, which would require the company to pass certain quality tests and assurances to continue operating. But congressional investigators say Massachusetts Board of Pharmacy did not take any action until "well over a year later."

__ In October 2004, the board sent a proposed consent agreement to Cadden, which would have included a formal reprimand and a three-year probationary period for the company's registration. The case ended without disciplinary action in 2006, when NECC agreed to a less stringent consent decree with the state.

FDA Commissioner Margaret Hamburg and Massachusetts Department of Public Health interim commissioner Lauren Smith are scheduled to testify at Wednesday's hearing.

According to the congressional report, lawmakers plan to ask the witnesses whether the FDA and state pharmacy board acted appropriately. Cadden is also scheduled to appear at the hearing, after lawmakers issued a subpoena to compel him to attend.

The NECC has been closed since early last month, and Massachusetts officials have taken steps to permanently revoke its license. The pharmacy has recalled all the products it makes, including 17,700 single-dose vials of a steroid that tested positive for the fungus tied to the outbreak.

Read More..

Microsoft's slide hits tech shares, but retailers gain

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France recognizes new Syria opposition

CAIRO/PARIS (Reuters) - France became the first European power to recognize Syria's new opposition coalition as the sole representative of its people and said on Tuesday it would look into arming rebels against President Bashar al-Assad once they form a government.


Twenty months into their bloody uprising against Assad, fragmented Syrian opposition groups struck a deal in Qatar on Sunday to form a broad coalition and their leader immediately appealed for European backing.


"I announce today that France recognizes the Syrian National Council as the sole legitimate representative of the Syrian people and as future government of a democratic Syria making it possible to bring an end to Bashar al-Assad's regime," French President Francois Hollande said, breaking ranks with European allies. Six Gulf Arab states took a similar step on Monday.


The question of arming the rebels would be looked at as soon as the rebel coalition formed a transitional government, Hollande told a news conference in Paris.


Arab League and EU foreign ministers meeting in Cairo on Tuesday welcomed the formation of the coalition as an important step forward, although their communiqué showed they had not reached a unanimous decision to recognize it as Syria's sole authority.


The French announcement came just hours after Syria's newly installed opposition leader urged European states to back the opposition so it could buy weapons.


Paris, one of Assad's harshest critics, had previously ruled out arming rebel forces, concerned that weapons could get into the hands of radical Islamists.


Speaking to Reuters as Arab and European ministers met to discuss Syria at the Arab League in Cairo, Mouaz Alkhatib, the Damascus preacher elected unopposed on Sunday to lead the new group, had asked for diplomatic backing.


"I request European states to grant political recognition to the coalition as the legitimate representative of the Syrian people and to give it financial support," he said.


"When we get political recognition, this will allow the coalition to act as a government and hence acquire weapons and this will solve our problems," added Alkhatib, who has been described by supporters as a moderate noted for his embrace of Syria's religious and ethnic minorities.


So far, concerted action on Syria has been thwarted by divisions within the opposition, as well as by big power rivalries and a regional divide between Sunni Muslim foes of Assad and his Shi'ite allies in Iran and Lebanon.


Russia and China, which have lent Assad diplomatic support since the uprising erupted in March last year, have shown no sign of warming towards his Western- and Arab-backed opponents.


"STEP FORWARD"


Cajoled by Qatar and the United States, the ineffectual Syrian National Council, previously the main opposition body based abroad, agreed to join a wider coalition on Sunday.


Britain's foreign minister, William Hague, said the coalition must show it had support within Syria before London would acknowledge it as the rightful government.


"If they have this, yes, we will then recognize them as the legitimate representative of the Syrian people," he told reporters at the Arab-European meeting in Cairo.


The opposition had hoped its new-found unity would clear the way for outside powers to arm the rebels, but Western nations fear such weapons could reach the hands of Islamist militants.


Western concern has also been heightened by documented reports of atrocities by ill-disciplined insurgents.


"Syria's newly created opposition front should send a clear message to opposition fighters that they must adhere to the laws of war and human rights law, and that violators will be held accountable," New York-based Human Rights Watch said.


BORDER VIOLENCE


Assad, whose family has ruled Syria for 42 years, has vowed to fight to the death in a conflict that has already killed an estimated 38,000 people and risks sucking in other countries.


His warplanes again struck homes in Ras al-Ain, a town on the northern border seized by rebels last week. Civilians fled over the border dividing it from the Turkish town of Ceylanpinar and thick plumes of smoke billowed upwards.


Syrian jets and artillery hit the town of Albu Kamal on the frontier with Iraq, where rebels have seized some areas, according to the mayor of the Iraqi border town of Qaim.


Tension also remained high on the Golan Heights, where Israeli gunners have retaliated against stray Syrian mortar fire landing on the occupied plateau in the previous two days.


Twenty months of conflict have created a vast humanitarian crisis, with more than 408,000 Syrians fleeing to neighboring countries and up to four million expected to need aid by early next year, according to the United Nations.


Fighting has also displaced 2.5 million civilians inside Syria, the Syrian Arab Red Crescent estimates.


"If anything, they believe it could be more; this is a very conservative estimate," Melissa Fleming, chief spokeswoman of the U.N. High Commissioner for Refugees, said in Geneva.


"So people are moving, really on the run, hiding," she told a news briefing. "They are difficult to count and access."


In Cairo, Arab League chief Nabil Elaraby urged opposition factions to join Alkhatib's group, formally known as the Syrian National Coalition for Opposition and Revolutionary Forces.


But although six Gulf Arab nations recognized the coalition as Syria's only legitimate representative on Monday, Iraq, Algeria and Lebanon prevented the League from following suit.


Iraq and Lebanon, with influential Shi'ite populations, have generally maintained better relations with Iran and with Assad, whose minority Alawite sect is an offshoot of Shi'ite Islam.


(Additional reporting by Shaimaa Fayed in Cairo and Jonathon Burch in Ceylanpinar, Turkey; Writing by Giles Elgood; Editing by Peter Graff)


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Windows Server Developers Can Now Use HP Cloud to Build, Deploy and Scale Their Applications
















I am happy to share that HP Cloud Compute now supports Microsoft Windows Server 2008 instances in addition to the variety of Linux distributions that are already available. Windows Server instances can now be launched in our US-West region. Since HP Cloud Compute is in public beta, all customers receive a 50% discount (see pricing below).



It is a priority for us to provide the tools that enable developers to quickly build, test, deploy and scale their applications in the cloud. That is why we created our CLI for Windows so that developers working in a Windows Server environment can quickly launch and manage their instances using the command line.













The three Windows Server images available are the Enterprise Editions of Windows Server 2008 SP2 (32 bit), Windows Server 2008 SP2 (64 bit) and Windows Server 2008 R2 (64 bit).  All Windows Server instances are created with a randomly generated password, which is then encrypted.  You can create and manage your Windows Server instances from our console, UNIX CLI and Windows CLI. For information about how to access your Windows Server instances using Remote Desktop (RDP), please review our documentation here.


The licenses for a Windows Server instance are included in the hourly rate for your instance, so you can spin up a server and get started without needing to worry about any additional licensing concerns.  Please see the table below for details about the hourly fees for both standard HP Cloud Compute Linux Instances and HP Cloud Compute Windows Server Instances.  While HP Cloud Compute continues in public beta, all customers receive a 50% discount off the prices listed below.























HP Cloud Compute Instance Types

Linux


(per hour)


Windows


(per hour)

Extra Small (1GB RAM, 1 core, 30GB disk)
$ 0.04
$ 0.06
Small (2GB RAM, 2 cores, 60GB disk)
$ 0.08 
$ 0.12
Medium (4GB RAM, 2 cores, 120GB disk)
$ 0.16
$ 0.24
Large (8GB RAM, 4 cores, 240GB disk)
$ 0.32
$ 0.48
Extra Large (16GB RAM, 4 cores, 480GB disk)
$ 0.64
$ 0.96
Double Extra Large (32GB RAM, 8 cores, 960GB disk)
$ 1.28
$ 1.92

Our team has been working hard to ensure that we are able to support all of your public cloud needs and appreciate all those that participated in our private and public betas.  We are very excited about the launch of Windows Server instances.  Stay tuned as we plan to launch support for additional versions of Windows Server including Windows Server 2012 in the coming months.  As always, feel free to leave a comment, connect with us on chat or email or find us on twitter (@hpcloud) if you have any questions.


Linux/Open Source News Headlines – Yahoo! News



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Scott Wolf Welcomes His Second Son

Former Party of Five star Scott Wolf and his wife Kelley have welcomed a son, Miller William Wolf. 

Wolf, 43, and his 35-year-old wife Kelley -- who starred in Real World: New Orleans -- told People.com their son was born on November 10, weighing in at 7 lbs., 6 oz.

RELATED GALLERY: Adorable Tots - Celebs and their Cute Kids!

The couple -- who wed in 2004 -- have another son, Jackson, 3.

"Jackson was a tough act to follow, the pair told People. "But so far Miller is nailing it."

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British medical journal slams Roche on Tamiflu

LONDON (AP) — A leading British medical journal is asking the drug maker Roche to release all its data on Tamiflu, claiming there is no evidence the drug can actually stop the flu.

The drug has been stockpiled by dozens of governments worldwide in case of a global flu outbreak and was widely used during the 2009 swine flu pandemic.

On Monday, one of the researchers linked to the BMJ journal called for European governments to sue Roche.

"I suggest we boycott Roche's products until they publish missing Tamiflu data," wrote Peter Gotzsche, leader of the Nordic Cochrane Centre in Copenhagen. He said governments should take legal action against Roche to get the money back that was "needlessly" spent on stockpiling Tamiflu.

Last year, Tamiflu was included in a list of "essential medicines" by the World Health Organization, a list that often prompts governments or donor agencies to buy the drug.

Tamiflu is used to treat both seasonal flu and new flu viruses like bird flu or swine flu. WHO spokesman Gregory Hartl said the agency had enough proof to warrant its use for unusual influenza viruses, like bird flu.

"We do have substantive evidence it can stop or hinder progression to severe disease like pneumonia," he said.

In the U.S., the Centers for Disease Control and Prevention recommends Tamiflu as one of two medications for treating regular flu. The other is GlaxoSmithKline's Relenza. The CDC says such antivirals can shorten the duration of symptoms and reduce the risk of complications and hospitalization.

In 2009, the BMJ and researchers at the Nordic Cochrane Centre asked Roche to make all its Tamiflu data available. At the time, Cochrane Centre scientists were commissioned by Britain to evaluate flu drugs. They found no proof that Tamiflu reduced the number of complications in people with influenza.

"Despite a public promise to release (internal company reports) for each (Tamiflu) trial...Roche has stonewalled," BMJ editor Fiona Godlee wrote in an editorial last month.

In a statement, Roche said it had complied with all legal requirements on publishing data and provided Gotzsche and his colleagues with 3,200 pages of information to answer their questions.

"Roche has made full clinical study data ... available to national health authorities according to their various requirements, so they can conduct their own analyses," the company said.

Roche says it doesn't usually release patient-level data available due to legal or confidentiality constraints. It said it did not provide the requested data to the scientists because they refused to sign a confidentiality agreement.

Roche is also being investigated by the European Medicines Agency for not properly reporting side effects, including possible deaths, for 19 drugs including Tamiflu that were used in about 80,000 patients in the U.S.

____

Online:

www.bmj.com.tamiflu/

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S&P 500 and Nasdaq inch higher, fiscal cliff a concern

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